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Because Q SA and Q SC represent an
2018-10-20
Because Q3SA and Q3SC represent an isogenic pair of iPSC lines from the same individual but with contrasting ATM genotypes (ATM−/− versus ATM+/−, respectively), we examined gene expression differences using RNA sequencing (RNA-seq), evaluating matches at the transcript level. Relatively few mRNAs we
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We obtained some evidence that NMD
2018-10-20
We obtained some evidence that NMD not only influences hESC fate through TGF-β and BMP signaling, but also through the WNT, FGF, and NOTCH pathways (Figure 2E). This raises the possibility that the ability of NMD to influence 5-lipoxygenase and mesoderm differentiation is a combinatorial process am
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In this study we tested the hypothesis that high RAD
2018-10-20
In this study, we tested the hypothesis that high RAD51 (-)-JQ1 and RAD51 foci activation is specifically associated with GSCs and that small-molecule inhibitors are effective GSC radiosensitizers. Results Discussion Identifying targets in the DDR pathway as a means to sensitize cancers to DN
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Hello world!
2018-07-29
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