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It is well established that a number of intracellular
2019-07-02
It is well established that a number of intracellular signaling pathways mediate sensitization of sensory neurons (Gold and Gebhart, 2010, Richardson and Vasko, 2002). This redundancy could be advantageous since it provides diversity in initiating and maintaining hypersensitivity in response to inju
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Only a few studies have examined
2019-07-02
Only a few studies have examined the effect of prostanoids on cardiac fibroblasts. Therefore, this study examines the effect of PGE2 on cardiac fibroblast proliferation and tests the hypothesis that PGE2 causes cardiac fibroblast proliferation via alterations of troglitazone regulatory molecules an
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br O GlcNAc transferase OGT belongs to the
2019-07-02
O-GlcNAc transferase OGT belongs to the metal-independent GT-B superfamily of glycosyltransferases, which has been well-reviewed previously [14,15]. OGT is an essential gene encoded on the X-chromosome, and it has two main regions: a long N-terminal tetratricopeptide repeat (TPR) region and a C-t
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Cyanine 5-dCTP Each of the CYP enzymes alluded
2019-07-01
Each of the CYP450 enzymes alluded to above are highly selective catalysts, in that, the three aryl coupling reactions en route the biosynthesis of 1 are catalyzed by three different CYP450 enzymes in a sequential manner (Fig. 1). In sharp Cyanine 5-dCTP is the recently described marine bacterial C
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In order to validate the ATP competitive mode of
2019-07-01
In order to validate the ATP competitive mode of inhibition, compound 12 was selected as a representative inhibitor of this series, and the IC50 values were determined at eight different concentrations of compound 12 ranging from 0.001 to 100 μM, and repeated four times using different ATP concentra
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br Acknowledgments This study was supported by a grant from
2019-07-01
Acknowledgments This study was supported by a grant from the National Science Council (NSC 98-2314-B-075B-007-MY2). Introduction Many complications may occur following treatment of femoral shaft open fracture such as nonunion, malunion, delay union, bone defect, bone and joint deformity or st
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While a large number of clinical trials have been completed
2019-07-01
While a large number of clinical trials have been completed or underway, there is a lack of strong evidence of their effectiveness and safety. Some experts pointed out that autologous transplantation may put patients at a risk of receiving the genetically defective immune cells, while allogeneic tra
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Pyoluteorin molecular Stimulated IUI is much more
2019-07-01
Stimulated IUI is much more effective than natural Pyoluteorin molecular or controlled ovarian hyperstimulation treatment. In four randomized trials of patients with unexplained subfertility, pregnancy rates were higher when IUI was performed in stimulated cycles than in natural cycles [odds ratio
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T wave alternans is a periodic beat
2019-07-01
T-wave alternans is a periodic beat-to-beat variation in the amplitude or morphology of the T wave on electrocardiography (ECG) (Fig. 1). Beat-to-beat T-wave alternans is considered to reflect increased dispersion of ventricular repolarization, and it is known to often precede the development of let
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Several cases of injury to the circumflex artery owing
2019-07-01
Several cases of injury to the circumflex artery owing to ablation of the lateral mitral isthmus and inside the CS have been reported. The circumflex artery and the CS share a close relationship. Takahashi et al. reported the first case of acute circumflex artery occlusion during CS ablation, which
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There is a concern about the possibility that
2019-07-01
There is a concern about the possibility that some patients with WPW syndrome who have LV dyssynchrony and atypical delta waves, as in the present case, may be diagnosed with DCM. In these WPW syndrome patients, although medical therapy might not improve LV dysfunction, RFCA of the AP might improve
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Several cases of injury to the circumflex artery owing
2019-07-01
Several cases of injury to the circumflex artery owing to ablation of the lateral mitral isthmus and inside the CS have been reported. The circumflex artery and the CS share a close relationship. Takahashi et al. reported the first case of acute circumflex artery occlusion during CS ablation, which
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Pero m s all del folclore
2019-07-01
Pero más allá del folclore, la conmemoración, con su ampulosidad y minucia, debía servir para medir la destreza virtuosa de los participantes, al exigir cierta competencia en la observancia de sus enigmas por parte de nuevos cristianos “ya bien enseñados en la Fe” (nos dice también Ávila) tras haber
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Although second malignancies are increasingly observed after
2019-07-01
Although second malignancies are increasingly observed after NHL, the incidence of CLL and RCC in the same patient is exceptional [4,5]. Nishikubo et al. [4] reported a case series of 8 patients with lymphoid malignancies and RCC. In 2 of 8 patients, CLL and T-cell CLL were diagnosed 1 year and 8 mo
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The Mexico City Policy is also
2019-06-29
The Mexico City Policy is also flawed on evidentiary and public health grounds. A 2011 study found that enforcement of the Mexico City Policy by the George W Bush administration led to an increase in abortion rates in sub-Saharan Africa, probably because of decreased contraception access and increas
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