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br Discussion As a previous report suggested invasive EMPD i
2018-10-29
Discussion As a previous report suggested, invasive EMPD is highly metastatic to lymph nodes (47%), and when metastatic lesions expand beyond the inguinal lymph node and have metastasized systemically, it is difficult to cure. For treatment, although radiotherapy is useful for local control of no
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br Conclusion br Introduction Since Br
2018-10-29
Conclusion Introduction Since Brånemark found that osseointegration occurred between titanium and bone in the mid-1960s, dental implants were introduced for the replacement of missing teeth, and treatment options for the partially or fully edentulous patient have expanded exponentially [1]. T
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In the present study the use of
2018-10-29
In the present study, the use of artificial saliva as a control medium is not included because it may alter the results as it was reported by Ref. [5] that saliva has a remineralization ability due to its supersaturation with Ca, P and F necessary for remineralization and the authors concluded that
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order 4EGI-1 br Discussion Neuroendocrine cells are distribu
2018-10-29
Discussion Neuroendocrine cells are distributed throughout the human body, including organs such as the gastrointestinal tract, pancreas, lung, thyroid, and adrenal glands. The largest population of neuroendocrine cells is located in the gastrointestinal tract. However, neuroendocrine tumors of t
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Introduction The application of minimally invasive spine sur
2018-10-29
Introduction The application of minimally invasive spine surgery (MIS) for treating thoracolumbar spine disorders and injuries has evolved rapidly, and the technical feasibility and safety of MIS has been well established. MIS can be defined as a spine operation based on the following basic princip
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br Maternal obesity high fat feeding The
2018-10-29
Maternal obesity/high fat feeding The prevalence of maternal obesity is increasing at an alarming rate [21], however, the consequences for the health of the offspring in later life is poorly understood compared with that of fetal undernutrition and fetal growth restriction. In various experimenta
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In addition the reduction of dehydrotheasinensin A
2018-10-29
In addition, the reduction of dehydrotheasinensin A to yield theasinensin derived from several paths. The formation of theasinensins through several chemical reactions was involved in EGCG oxidation [35,37,43]. Dehydrotheasinensin A could be reduced by the reductants such as ascorbic lipoxygenase o
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Phytochemicals including polyphenols and saponins are promin
2018-10-29
Phytochemicals including polyphenols and saponins are prominent for their diverse health benefits including antioxidant and antidiabetic activities [44]. In this study, polyphenolics (total phenolics, tannins and total flavonoids) and total saponins were quantified in B. eurycoma and D. microcarpum
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Vadimezan Differentiating ESCs adopt an anterior rostral neu
2018-10-29
Differentiating ESCs adopt an anterior (rostral) neural character both in the absence of exogenous growth factor stimulation and also upon the blockade of mesendoderm signaling by exogenously added inhibitors (Elkabetz et al., 2008; LaVaute et al., 2009; Pankratz et al., 2007; Smukler et al., 2006;
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br Long term maintenance of hPSCs
2018-10-29
Long term maintenance of hPSCs in a scalable and defined suspension culture system A report published recently in Stem Cell Research (Chen et al., 2012, 8:388–402) extends from these previous studies to demonstrate for the first time, the long term expansion of hESCs retaining the characteristic
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br Introduction Stem cell divisions resulting in alternative
2018-10-29
Introduction Stem cell divisions resulting in alternative pathways of self-renewal or differentiation require very distinctive epigenetic regulation of gene expression from the same genome. Where division has a symmetrical output of progeny cells, the assumption is that the molecular signatures d
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br Introduction Human embryonic stem
2018-10-26
Introduction Human embryonic stem cells (hESCs), with the capacity to give rise to all the somatic tissues and germ cells, provide a valuable tool for both basic research and future regenerative medicine (Thomson et al., 1998). However, during in vitro maintenance genomic abnormalities can accumu
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purchase N6022 At present the strategies for direct generati
2018-10-26
At present, the strategies for direct generation of iNSCs from somatic purchase N6022 can be broadly classified into two groups according to whether the procedure passes through intermediate or pluripotent state. Lujen et al. generated iNSCs from fibroblasts by introducing Brn2, Sox2, and FoxG1; bu
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Cardiac MRI was performed to assess potential changes in car
2018-10-26
Cardiac MRI was performed to assess potential changes in cardiac function due to teratoma growth. For this, a subacute model with cell delivery 4 days after ischemia reperfusion injury was chosen since functional improvements following the transplantation of human ESC-CMs have been reported for this
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Several approaches exist to prevent allogeneic cell
2018-10-26
Several approaches exist to prevent allogeneic cell transplantation-related immune rejection. One is immune suppression therapy using a combination of several different types of immunosuppressants. Others are the use of major histocompatibility complex (MHC)-matched donor cells to reduce immunogenic
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