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Insulitis is the predominant pathological feature in
2018-11-07
Insulitis is the predominant pathological feature in pancreatic islets of T1D subjects caused by the infiltration of autoimmune CD8+ and CD4+ T cells, CD20+ B cells, and macrophages (Campbell-Thompson et al., 2013; In\'t, 2011). TCM ryanodine trafficking in peripheral blood maintain the capacity to
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This study is limited in that the metabolomic abnormalities
2018-11-07
This study is limited in that the metabolomic abnormalities described in children in Malawi may not be generalizable to other populations due to differences in diet, environment, socioeconomic factors, and other variables. The Metabolon HD4 platform provides wide coverage of many metabolic pathways,
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br Results The study flow diagram is shown in Fig
2018-11-07
Results The study flow diagram is shown in Fig. 1. Baseline characteristics of patients included in the final analysis are shown in Table 1. There were 197 patients treated with IPI and 65 treated with a BRAFi who had pretreatment CBC available. Median time from baseline CBC to first dose of trea
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Antigen Rv is a secretory antigen and a virulence factor
2018-11-07
Antigen Rv0577 is a secretory antigen and a virulence factor associated with the replication of M. tuberculosis. The antigen is an agonist of Toll-like receptor 2 (TLR2) and can promote maturation of dendritic cells (Byun et al., 2012). Rv2875 encodes a cell membrane-associated antigen, MPT70, of M.
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Viral diseases due to Monodon
2018-11-07
Viral diseases due to Monodon Baculovirus (MBV) and Hepatopancreas Parvovirus (HPV) in hatchery reared larvae have been reported in India [6,36,24]. Although MBV is relatively well tolerated by P. monodon[5] it has been implicated in mass mortalities in shrimp cultured at high densities [10]. Infect
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br Specification Table br Value of the data br
2018-11-07
Specification Table Value of the data Data Here, we present data regarding the effect of mitochondrial fission inhibition on skeletal muscle differentiation. Although similar experiments have been published by others [1,2], the data presented here support and add to the conclusions made by
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Data The dataset of this article provides
2018-11-07
Data The dataset of this article provides information on the abundance of ant taxa in the cultivated plants intercropped with the plantain and the weevil damages. The Figs. 1–7 show the abundance of ant taxa in the crops associated to plantain. Table 1 shows the weevil damage. Experimental desig
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The fundamental challenge scientifically is how to
2018-11-07
The fundamental challenge, scientifically, is how to simplify, but not to -simplify. On the one hand, scientific progress requires parsing complexity, ideally into falsifiable hypotheses that can be addressed within well-designed empirical studies. On the other hand, slicing too narrowly is likely t
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Two key findings are as follows First
2018-11-07
Two key findings are as follows: First, motor threshold values do not differ in individuals with TS relative to matched controls (Orth, 2009) (c.f. reference (Orth and Rothwell, 2009)). Importantly, it is suggested that equivalent RMTs in TS patients and controls indicates that neural populations re
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In addition individuals who experienced CSA
2018-11-07
In addition, individuals who experienced CSA and who develop CSA-related Post-Traumatic Stress Disorder (PTSD) are at increased risk to develop subsequent internalizing disorders (Lindert et al., 2014), which makes internalizing disorders and CSA-related PTSD overlapping in symptomatology. This, in
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Similarly in human participants there is evidence of hippoca
2018-11-07
Similarly, in human participants, there is evidence of hippocampal activation as measured by magnetoencephalography (MEG) during performance of transverse patterning (Hanlon et al., 2003; Moses et al., 2009). Interestingly, hippocampal activity decreased and MTL cortical activity increased when sema
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Some groups have reported a history of smoking having a
2018-11-06
Some groups have reported a history of smoking, having a BMI of less than 23 kg/m2, previous unilateral inguinal hernioplasty, postoperative anastomotic stricture, and prolonged use of self-retaining retractor during operation as risk factors of post-RP IH formation. However, Abe et al reported that
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br Discussion Several organ systems can be
2018-11-06
Discussion Several organ systems can be affected by marathon running. Most problems that have been mentioned involve the musculoskeletal, gastrointestinal, cardiac, renal, and pulmonary systems, and also include electrolyte and fluid imbalance, but seldom soft-tissue infections. Because marathon
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br Results Three cases were diagnosed as TEN associated with
2018-11-06
Results Three cases were diagnosed as TEN associated with M. pneumoniae and two were diagnosed as TEN associated with herpes simplex virus infection (Table 2). The presence of these viruses was confirmed by positive serologic findings. The patients consisted of three boys and two girls, with an a
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Radiological investigations are nonspecific and may
2018-11-06
Radiological investigations are nonspecific and may mimic various other benign or malignant conditions. Numerous other diseases show lesions of a variable density with a peripheral enhancement on abdominal CT scans. Areas of focal calcification and liquefactive necrosis, indicating simultaneously e
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