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On the other hand controlling shareholders
2018-11-03
On the other hand, controlling shareholders can elect their representative(s) to the board of directors who will appoint a manager that will act in their self-interest. Jensen and Meckling (1976) and Shleifer and Vishny (1986) demonstrate that controlling shareholders can impose greater monitoring o
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br Conclusions Despite there has
2018-11-03
Conclusions Despite there has been an increased amount of research on “sustainable transportation”, most individual authors, entities, and agencies still do not have an agreed-upon definition of “sustainable transportation”. This poses challenges to the review of existing literature and to the pr
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order (RS)-CPP Competitions for healthcare facilities tend t
2018-11-02
Competitions for healthcare facilities tend to be by invitation only. Do sponsors fear an open submissions process will unleash the floodgates to unqualified firms and unbuildable submittals, therefore undermining the sponsor׳s ROI? Pre-selection, coupled with costly entry eligibility requirements,
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Appendiceal perforation following BTA noted in our
2018-11-02
Appendiceal perforation following BTA noted in our two cases may have occurred because of appendicolith dislodgement at the moment of injury. An appendicolith (appendiceal calculi, appendiceal enterolith, or appendiceal lithiasis) is a conglomeration of firm, dense feces with some mineral deposits.
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br Results There were pediatric surgeries in group
2018-11-02
Results There were 365 pediatric surgeries in group I and 630 pediatric surgeries in group II (including 343 surgeries performed by a PS, Table 1). In group I, most surgeries were performed by general surgeons (GS, 37.5%) and urologists (GU, 35.9%), while a smaller portion were performed by otola
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An year old man presented
2018-11-02
An 87-year-old man presented with abrupt, severe lower abdominal pain and a pulsatile right hip mass. The patient had had chronic obstructive pulmonary disease and benign prostate hyperplasia for more than 2 decades. The patient had frequent bursts of vigorous productive coughing associated with his
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br Discussion Delayed expansion of a contralateral EDH after
2018-11-02
Discussion Delayed expansion of a contralateral EDH after decompressive surgery for an acute SDH is rare, with an incidence ranging from 1.3% to 5.7%. In the literature, the longest period for an occurrence of the enlargement of a delayed contralateral EDH following the initial surgery is 4 days,
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RG7388 Introduction Coronary artery disease CAD is
2018-11-02
Introduction Coronary artery disease (CAD) is a major cause of morbidity and mortality in patients with end-stage renal disease (ESRD). Despite the development of revascularization therapies and refinement of surgical techniques in past decades, the prognosis of patients with ESRD remains poor; the
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The maximum settling time examined in our study was min
2018-11-02
The maximum settling time examined in our study was 90min, but oocyst sedimentation would probably continue if the settling time was extended resulting in increased oocyst reduction. A time estimate required for all oocysts to reach the bottom of the glass jars was calculated as 3.6h in treated wate
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br Introduction Skeletal muscle development is carried out b
2018-11-02
Introduction Skeletal muscle development is carried out by a reservoir of progenitor cells, which differentiate and fuse into multinucleated syncytia during several distinct but overlapping stages: early embryonic, mid-late embryonic, fetal, perinatal and adult (for review see Tajbakhsh, 2009). F
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Our previous study showed that miR
2018-11-02
Our previous study showed that miR-210 was highly expressed in neural precursor niclosamide (NPCs) under hypoxic conditions (Liu et al., 2011). To further understand the role of miR-210 in NPCs, TargetScan was used to search for miR-210 putative target genes. Based on conserved seed sequences and t
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Respiratory chain complexes are organized into
2018-11-02
Respiratory chain complexes are organized into higher oligomeric structures called supercomplexes or respirasomes. In mammalian cells, complex I (NADH:ubiquinone oxidoreductase) is associated with dimeric complex III (ubiquinol:cytochrome c oxidoreductase) and multiple copies of complex IV (cytochro
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Talabostat mesylate Another practical advantage of the
2018-11-02
Another practical advantage of the system is its relative low cost. The high price of current commercially available serum-free media such as StemPro and mTeSR always hinders the universal application of the scale-up technologies for hiPSC expansion, especially for xeno-free media when albumin is re
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Kearns et al demonstrated that dCas
2018-11-02
Kearns et al. (2014) demonstrated that dCas9 transcriptional activators and repressors can be used to control human pluripotent stem cell differentiation by targeting endogenous SOX17 and OCT4. We have expanded the target gene list to additional key factors in the endodermal and pancreatic different
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br Results br Discussion This study describes
2018-11-02
Results Discussion This study describes a simplified protocol for the efficient generation of hiNSCs via direct reprogramming. hiNSC lines grow as colonies on MEF feeder layers. Like hESCs, hiNSCs stain positive for pluripotent transcription factors OCT4, SOX2, and NANOG, but do not express ce
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