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Here we ablated Tsc in BM MSCs
2018-11-09
Here, we ablated Tsc1 in BM-MSCs and monocytes, as well as in their progenies, OBs and OCs, and found that mTOR regulates bone size in length and width by coordinating MSC proliferation and differentiation, and bone quality by suppressing osteoclastogenesis and bone resorption in cell-autonomous man
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aminopeptidase inhibitor br Genetic methods of opsin gene
2018-11-09
Genetic methods of opsin gene delivery to specific neural populations Opsin genes can be selectively expressed in a specific pre-chosen type of neurons in the brain. Let us discuss the main strategies whose efficiency has been proved to achieve in vivo expression. One of the most widespread metho
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There was an attempt to explain
2018-11-09
There was an attempt to explain the physiological meaning of the balance between the oligomeric and the monomeric forms of the sigma-1 receptor by the hypothesis that oligomerization of the sigma-1 receptor regulates its ligand-mediated functions [57]. Presumably, the sigma-1 receptor ligands can in
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The null findings for mortality
2018-11-09
The null findings for mortality stand in trifluoperazine hydrochloride with prior work that has found variation in mortality rates according to state and county characteristics (Cullen et al., 2012; Kochanek, Murphy & Xu, 2015). These previous studies, however, examined the relationship between mor
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br Methods br Discussion We systematically searched the
2018-11-09
Methods Discussion We systematically searched the literature from the last five years to identify potential blood biomarkers for cancer (Hanahan & Weinberg, 2011; Cree, 2011). The data mining process retrieved 3990 citations from the initial 19, 724 records, screening the abstracts of these ci
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Substantial epidemics and sporadic outbreaks of
2018-11-09
Substantial epidemics and sporadic outbreaks of hepatitis E occur in tropical and sub-tropical countries (e.g., in India, Uganda, Sudan, and Mexico), with up to tens of thousands affected (Dalton et al., 2013; Kamar et al., 2012). Approximately two billion people (one-third of the world population)
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Given the present data we are not
2018-11-09
Given the present data, we are not able to explain why the left auditory trp channels was overactivated during 80-Hz ASSR stimulation. However, the left and right transverse temporal gyri and left planum temporale have some differential cytoarchitectonic features (Seldon, 1981; Hutsler and Gazzanig
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The succesful development of flavivirus vaccines began years
2018-11-09
The succesful development of flavivirus vaccines began 80years ago in 1937 with the yellow fever YFV17D live-attenuated vaccine (Monath, 2008). Since then, >600 million people have been vaccinated, with 98% protection and a >10year persistence of vaccine–induced immunity (Barrett and Teuwen, 2009).
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Notably a recent training study asked
2018-11-09
Notably, a recent training study asked 6 years old preschoolers to learn grapheme to phoneme correspondence. Although these children had already acquired some letter knowledge (10 upper case letters and 5.8 lower case letters) prior to training, they did not possess neural tuning for words associate
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UMI-77 Supplier br Materials and methods br
2018-11-09
Materials and methods Results and discussion Conclusion Our previous publications have established a five month-long stable C-FBN-C on a microelectrical array as a C-FBN-biosensor [10,11] and characterized it pharmacologically by investigating its responsiveness to Mg, TTX, and VER ([12], i
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En estas condiciones lo que se impone es llevar tan
2018-11-09
En estas condiciones, lo que se impone es llevar tan lejos como sea posible un persistente esfuerzo democratizador que permita politizar, centralizar y coordinar las decisiones económicas clave, superando definitivamente los rígidos condicionamientos que el capital hoy día impone sobre el desarrollo
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No obstante al rendimiento por hect rea de riego se
2018-11-09
No obstante, al rendimiento por hectárea de riego se le compara con el que se obtiene en condiciones de temporal, propiamente dicho. Así, se tiene que: Al realizar dicha comparación, entre el rendimiento obtenido por hectárea de riego respecto del de temporal, aparte de pasar por alto principios de
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br La frontera norte de M xico La frontera norte
2018-11-09
2. La frontera norte de México La frontera norte de México (fnm) es una región que se caracteriza por un desarrollo económico avanzado comparado con la frontera sur del mismo país e incluso con algunas ciudades del centro de la República Mexicana. El sector maquilador manufacturero, comercial y d
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In pluripotent cells phosphorylation has
2018-11-08
In pluripotent cells, phosphorylation has a central role in directing cell identity by relaying growth-factor signaling through key pathways (i.e., fibroblast growth factor [FGF] and transforming growth factor β [TGF-β]) (Chen et al., 2011; Singh et al., 2012a; Vallier et al., 2005; Yu et al., 2011)
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br Results br Discussion In the field of
2018-11-08
Results Discussion In the field of stem cell research, the demand for standardized media is rising, allowing for better reproducibility of results and thereby deepening our knowledge of the pathways regulating their maintenance and differentiation. Here, we set out to determine the minimum req
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