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semagacestat Strengths of this analysis include that
2018-11-13
Strengths of this analysis include that the biomarker assay was analytically validated, the data were from a randomized clinical trial, and the hypothesis was prospectively stated prior to data unblinding (Khleif et al., 2010). The fact that a single biomarker was identified minimized the potential
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Disclosure br Introduction The proteasome inhibitor PI Borte
2018-11-13
Disclosure Introduction The proteasome inhibitor (PI) Bortezomib is used as a first- and second-line treatment of multiple myeloma (MM) (Anderson et al., 2011). Proteasomes\' (Finley, 2009; Lander et al., 2012) main function is to degrade ubiquitinated proteins in a controlled manner (Bedford et
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br Results Patients with AISC were significantly younger tha
2018-11-13
Results Patients with AISC were significantly younger than those with PSC and IBD (Table 1). Immunosuppressants and ursodeoxycholic PalMitoyl Tripeptide-1 were commonly used in the liver patients, but not in the IBD groups, but otherwise the demographic details of patients with AISC and PSC at t
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br Conflict of interest statement br
2018-11-13
Conflict of interest statement Author contributions The following are the supplementary data related to this purchase HBTU article Acknowledgements We thank the NIAID Tetramer Facility (Emory University, Atlanta, GA) for supplying CD1d tetramer and Dr. T. Camou (National Reference Laborat
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br Introduction Mantel cell lymphoma
2018-11-12
Introduction Mantel cell lymphoma (MCL) is a rare B-cell non-Hodgkin\'s lymphoma with a poor long-term prognosis. Skin involvement occurs in only 2–6% of all cases of MCL, but is seen in 17% of stage IV patients. It is important for the dermatologist to realize and master the primary clinic prese
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Actually there was more attention to the effect of
2018-11-12
Actually, there was more attention to the effect of CsA on GO that have been clearly demonstrated. Hence, in this investigation we tried also to focus on TAC as well. To our knowledge this comparative immune-histochemical investigation using this group of cytokines has been not previously attempted
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Introduction Fat embolism syndrome FES is characterized by t
2018-11-12
Introduction Fat embolism syndrome (FES) is characterized by the onset of respiratory, neurological, cutaneous, and hematologic manifestations and is thought to be related to intravascular embolization of fat. FES has been associated with bone marrow necrosis in patients with hemoglobinopathies; ho
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br Conclusion br Acknowledgments br Introduction A baumannii
2018-11-12
Conclusion Acknowledgments Introduction A. baumannii is a leading cause of nosocomial bacteremia, severe pneumonia, meningitis, infections of the urinary tract, bloodstream and other parts of the body. The emergence of sharply increasing rate of Multidrug-resistant A. Baumannii (MDRAB) infe
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Based on these previous studies we hypothesized that
2018-11-12
Based on these previous studies, we hypothesized that reanalysis of the ASHRAE RP-884 database according to climate would clarify any differences in thermal selective estrogen receptor modulators among climates. We determined that it is relevant to identify climates in defining the adaptive model b
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Once the castle was constructed Firuz
2018-11-12
Once the castle was constructed, Firuz Bey was assigned as the commander of the few soldiers in the castle. He was given the authority to control the ships that passed the bosphorus in front of the castle. The ships were forced to pay a certain amount of tax, and those who refused to pay were sunk b
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The Carapace at Castelbuono Estate Winery is perfectly repre
2018-11-12
The Carapace at Castelbuono Estate Winery is perfectly representative of biomorphic and zoomorphic architecture. The winery is located in the municipality of Bevagna in Perugia, Italy. The Carapace (Figure 1), which was inaugurated in June 2012, was designed by world-famous sculptor Arnaldo Pomodoro
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Most important the archaeological excavations brought to
2018-11-12
Most important, the archaeological excavations brought to light the northern foundation walls of the Temple beneath the facade of the Palazzo Caffarelli. The foundation was aligned, as Lanciani had envisioned, with the slanted side of the court. The huge structure, 4.30m thick, crosses the southern
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myd88 signaling br Risks of malignancy Risk factors for mali
2018-11-12
Risks of malignancy Risk factors for malignancy in substernal goiters may include old age, a family history of thyroid pathology, a history of cervical radiation therapy, recurrent goiter, and the presence of cervical adenopathy, thrombotic material within the lumen of a vein in contact with a su
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br Discussion Based on a literature
2018-11-12
Discussion Based on a literature review, it is stated that there are two requirements for tension pneumocephalus to develop after a VP shunt: the presence of a CSF diversion system causing a decrease in intracranial pressure and the existence of a craniodural defect. In the presence of a craniodu
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br Case Report A year old woman
2018-11-12
Case Report A 73-year-old woman presented with symptoms of massive hematochezia and abdominal pain. Her blood pressure was 116/58 mmHg, pulse rate 78 beats/min, and temperature 36.4°C. Abdominal examination revealed: distension, board-like rigidity, and muscular defense in the right upper quadran
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