Because Q SA and Q SC represent an

2018-10-20

Because Q3SA and Q3SC represent an isogenic pair of iPSC lines from the same individual but with contrasting ATM genotypes (ATM−/− versus ATM+/−, respectively), we examined gene expression differences using RNA sequencing (RNA-seq), evaluating matches at the transcript level. Relatively few mRNAs we

We obtained some evidence that NMD

2018-10-20

We obtained some evidence that NMD not only influences hESC fate through TGF-β and BMP signaling, but also through the WNT, FGF, and NOTCH pathways (Figure 2E). This raises the possibility that the ability of NMD to influence 5-lipoxygenase and mesoderm differentiation is a combinatorial process am

In this study we tested the hypothesis that high RAD

2018-10-20

In this study, we tested the hypothesis that high RAD51 (-)-JQ1 and RAD51 foci activation is specifically associated with GSCs and that small-molecule inhibitors are effective GSC radiosensitizers. Results Discussion Identifying targets in the DDR pathway as a means to sensitize cancers to DN

Hello world!

2018-07-29